Synthesis, characterization and antibacterial activity of cyclohexyltin N-(salicylidene)valinates

Laijin Tian

Abstract


Abstract: Two new cyclohexyltin N-(salicylidene)valinates, [2-HOC6H4CH=NCH(CH(CH3)2)COO]SnCy3 (1) and [2-OC6H4CH=NCH(CH(CH3)2)COO]SnCy2 (2) (Cy = cyclohexyl), have been synthesized and characterized by elemental analysis, IR, and 1H NMR. The crystal structure of 2 has been determined by X-ray single crystal diffraction. In the complexes, the carboxylate is monodentate. Complex 1 is a four-coordinated tin compound, and 2 has a distorted trigonal bipyramidal geometry with the axial locations occupied by one carboxylate oxygen and a phenolic oxygen of the ligand. Bioassay results show that 1 and 2 have good in vitro antibacterial activity against Escherichia coli.

Full Text: PDF

Refbacks

  • There are currently no refbacks.