1.1.5. Synthesis and characterization of silver(I) complexes with ligands having anti-inflammatory properties
AbstractFive water soluble silver(I) complex with Ibuprofen (AgIbu), Naproxen (AgNap), Mefenamic acid (AgMef), acetyl salicylic acid(AgAsp) and salicylic acid (AgSal) were synthesized and characterized by elemental analysis, FT-IR, 1H and 13C NMR. Data suggest coordination of the ligand to Ag(I) through the oxygen atom of the carboxylic group. AgAsp was obtained as a mixture of AgAsp and Ag(I)-2-hydroxybenzoate (AgSal) due to decomposition by thermal and hydrolysis of acetylsalicylic acid into salicylic acid. AgSal structure was confirmed by FT-IR, NMR and X-ray diffraction. Synthesized compounds were tested toward UV-radiation (258 nm, 30 W) and compared with AgCl in order to characterize their light sensibility.
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P. Levin, N. Dinamarca, G. Gómez, A. Ibañez, M.T. Garland and M. A. Paez, M. I. A. H. M. (1). 1.1.5. Synthesis and characterization of silver(I) complexes with ligands having anti-inflammatory properties. Communications in Inorganic Synthesis, 1(1). https://doi.org/10.21060/cis.v1i1.1465